Fri Jul 25 2025

27 articles - From Friday Jul 18 2025 to Friday Jul 25 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Inflamm Bowel Dis

A Systematic Review and Meta-Analysis of Animal Models on the Possible Link Between Periodontitis and Inflammatory Bowel Diseases.

Inoculation with the periodontitis-associated bacteria F. nucleatum and probably also P. gingivalis exacerbates experimental colitis in mice. It is yet unclear whether colitis can affect periodontal health and/or disease.

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Pancreatology

Obesity is a major risk factor for adverse outcomes following Pancreatectomy: Results of a systematic review and meta-analysis.

The meta-analysis of best possible evidence indicates that obesity is associated with increased morbidity and mortality following pancreatic resection and should be included in risk predication models for short-term outcomes after pancreatic resections. Impact of different sub-types of obesity on outcomes requires further research.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Plasma chylomicron-rich lipidomic and fatty acid profile following a meat or analogue meal in healthy males: a randomized controlled trial.

There are subtle differences in the lipid response to beef, lamb and PMBA containing meal. as NCT04545398.

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The 2018 World Cancer Research Fund /American Institute for Cancer Research Score and Cancer Risk: Results from the Diabetes Prevention Program Outcomes Study.

Alignment with WCRF/AICR Recommendations may lower cancer risk in adults with prediabetes and type 2 diabetes, highlighting the importance of considering lifestyle factors for cancer prevention.

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The Interplay of Nutritional Status and Physical Function on Health Outcomes in Older Adults: A Longitudinal Study in Singapore.

Both nutritional status and physical function are independently and interactively associated with health outcomes in older adults. These findings underscore the need for integrated interventions targeting both nutritional status and physical function to promote healthy aging and reduce frailty. Future research should explore the mediating role of physical function and evaluate strategies to optimize health outcomes in older adults.

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Inflamm Bowel Dis

Efficacy and Safety of Ustekinumab and Vedolizumab for Crohn's Disease of the Pouch.

In one of the largest cohorts evaluating UST and VDZ for CD of the pouch thus far, these biologics were found to be safe and effective treatments for CD of the pouch.

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J Crohns Colitis

Day 3 Oxford Criteria Predict Steroid non-response for Acute Severe Ulcerative Colitis in the Post Biologic Era.

Day-3 Oxford criteria was an independent predictor of steroid non-response. The risk of colectomy remains substantial after discharge despite low in-hospital colectomy rate following an episode of ASUC. Initial steroid response did not affect long-term colectomy rate at 12 months.

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Efficacy and Safety of Upadacitinib Maintenance Therapy in Patients with Moderately to Severely Active Crohn's Disease: 2-Year Results from the U-ENDURE Long-Term Extension Study.

Sustained clinical, endoscopic, quality-of-life, and biomarker outcomes were observed in patients who were initial responders to upadacitinib and completed 2 years of maintenance therapy, with no new safety signals identified. Clinical trial identifier U-ENDURE; ClinicalTrials.gov number, NCT03345823.

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Spatiotemporal analysis of Crohn's disease reveals PECAM2 signaling at the basis of inflammation-to-fibrosis transition.

Our results provide insights into CD38-driven fibrosis and indicate that PECAM2 signaling blockade could reduce the development of strictures in patients with Crohn's disease, potentially offering a new treatment target.

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Liver Transpl

A novel, institutionally developed hypothermic oxygenated machine PErfusion system allows low-cost, universal implementation for liver transplantation: A safety and feasibility pilot study.

The total cost of the COARO system is US$1,494.87 per LT, 80% cheaper than a commercial equivalent. The COARO system is safe and presents significant economic advantage over commercial systems, allowing universal implementation of HOPE for al LT procedures in under resourced units.

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Cognitive dysfunction, psychiatric distress, and functional decline after liver transplantation.

Below-expectation cognition was prevalent among 25% of liver recipients at least 1 year after transplant and was associated with a higher likelihood of reporting psychiatric distress. These findings underscore the need for longitudinal assessment of cognitive and mental health outcomes among recipients of liver transplants.

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Pancreas

Significance of Pancreatic Steatosis as a Predictor of New-Onset Diabetes Mellitus Following Pancreatectomy.

Preoperative remP/S ratio and HbA1c were significant predictors of NODMP, enabling the effective stratification of NODMP risk and facilitating the early treatment of the disease.

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Pancreatology

Predictors of acute pancreatitis in patients treated with GLP-1 receptor agonists for weight management.

A history of gallstone disease, history of AP, CAD/PVD, and tobacco use were associated with AP after initiation of GLP-1RA for obesity treatment. A higher BMI appears to be protective against AP. Recognizing factors associated AP after GLP-1RA initiation can inform clinicians on risk stratification.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Biomarkers for individualized nutritional therapy in disease-related malnutrition: A narrative review.

It is crucial to use biomarkers to distinguish etiology at an individual level when implementing nutritional treatment interventions. The key challenge ahead is to determine the most effective way to incorporate these biomarkers into established assessment tools, optimizing personalized nutritional care for patients with malnutrition.

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Inflamm Bowel Dis

Breaking Conventions: Innovative Reflections on the Medication Use Research of Inflammatory Bowel Disease in Adults and the Elderly.

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Comment On: Predictors of Complicated Disease Course in Children and Adults With Ulcerative Colitis: A Nationwide Study From the epi-IIRN.

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J Crohns Colitis

Comparison of the FDA and EMA guidance on drug development in ulcerative colitis: an expert panel review.

Harmonizing FDA and EMA guidelines is essential to streamline global IBD clinical trials, reduce redundancies, and improve patient outcomes. Recommendations include adopting less invasive assessments, standardizing remission definitions, and prioritizing patient-centered endpoints. These measures could reduce trial complexity, increase inclusivity, and accelerate the development of effective therapies for UC.

Pubmed   Journal   ReadQx   PMC

Pancreatology

Fragments of Truth: AI-nCLE and the Mirage of Universal Benefit.

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Glucagon-like peptide-1 receptor agonists (GLP-1RA) and acute pancreatitis.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Mucosal Responses to Type II Interferon in IBD.

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Liver Transpl

Calcium in your arteries: Abdominal, coronary, or both to predict post-LT MACE?

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Centers for medicare and medicaid's new transplant program requirements may unintentionally limit access'.

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Comparative analyses of anastomosis methods for dual portal vein right lobe grafts in living donor liver transplantation: A retrospective study.

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Fellows' Corner.

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Pancreatology

Comparative efficacy of paracetamol and tramadol for pain management in acute pancreatitis: A double-blinded randomized study.

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Comparison of early and delayed intervention for symptomatic acute necrotizing pancreatitis: Need for Re-intervention and clinical outcomes.

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Letters&Replies

Letters to the editors and authors’ replies

Inflamm Bowel Dis

REPLY: Breaking Conventions: Innovative Reflections on the Medication Use Research of IBD in Adults and the Elderly.

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